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UK researcher leads global ruminant genetics revolution

UK researcher leads global ruminant genetics revolution


By Blake Jackson

A University of Kentucky researcher is at the forefront of a global effort to revolutionize agriculture and conservation.

Theodore Kalbfleisch, an associate professor at the Martin-Gatton College of Agriculture, Food and Environment (CAFE), is part of the Ruminant Telomere-to-Telomere Consortium (RT2T). This ambitious project aims to create complete and accurate genetic maps for various cud-chewing animals, including cattle, sheep, goats, and deer.

Historically, studying the genetics of ruminants has been hindered by incomplete and fragmented genome data. However, the RT2T is using advanced sequencing technology to overcome these challenges. By mapping entire genomes, including previously inaccessible regions, researchers can unlock a wealth of information about genetic traits and behaviors.

"By achieving a complete understanding of the genome structure of these animals, we can unlock new ways to enhance breed quality, disease resistance, and overall productivity," said Kalbfleisch. "These are crucial for the sustainability of the agricultural sector."

The project, detailed in Nature Genetics, has far-reaching implications. For agriculture, it promises to accelerate the development of improved breeds with higher milk production, better wool quality, and increased disease resistance.

For conservation, comprehensive genomic data can help identify genetic vulnerabilities in endangered species and inform effective breeding strategies.

To maximize the impact of this research, the RT2T adopts an open science approach, making data freely accessible to the global research community.

This collaborative model fosters innovation and ensures that benefits reach farmers, breeders, and conservationists worldwide.

"The open collaboration model allows researchers from around the world to contribute to and benefit from this massive pool of genetic information," Kalbfleisch said. "It benefits scientific advancements and ensures they have a broad and lasting impact."

Kalbfleisch and his colleagues at UK CAFE are playing a pivotal role in interpreting the vast amount of data generated by the RT2T.

Their work will provide insights into the evolutionary history of ruminants and inform breeding programs that enhance livestock resilience and productivity.

"Looking ahead, this research's implications for the agricultural sector are significant," Kalbfleisch said. "It could potentially revolutionize livestock management practices and conservation efforts. Farmers and breeders will have access to powerful genetic tools that can inform breeding decisions, leading to healthier and more productive livestock."

Ultimately, the RT2T project has the potential to transform agriculture and conservation, ensuring a sustainable future for both humans and animals.

Photo Credit: gettyimages-r-j-seymour

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Categories: Kentucky, Education, Livestock

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