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Influenza D: The Next Pandemic?

Influenza D: The Next Pandemic?


Dr. Feng Li, a virologist at the University of Kentucky Martin-Gatton College of Agriculture, is researching influenza D, an enigmatic pathogen with the potential to spread from animals to humans.

Li's investigations reveal cattle are the primary transmitters of the lesser-known influenza D virus, with occasional spillover to other animals like goats, buffalo, and sheep. Human exposure has also been observed, especially among individuals working on cattle farms.

The core objective of Li's research is to unravel the mysteries surrounding influenza D and determine its ability to infect humans. By studying the virus's tissue and host tropism, as well as its infection biology, he aims to gain crucial insights into its behavior. Li and his team have conducted experiments using ferrets as a model for human influenza, aiming to assess the potential for cross-species transmission.

Unlike influenza A and B, there is currently no vaccine available for influenza D, and it is not included in annual surveillance programs. Li emphasizes the need for active surveillance and monitoring to detect any mutations that could enhance the virus's ability to infect humans.

The ongoing COVID-19 pandemic and the mutation of avian influenza underscore the importance of proactive research and vigilance in mitigating outbreaks and pandemics. Li emphasizes the need to approach the topic with caution and gather essential data to establish safeguards against potential threats.

Influenza D poses an intriguing challenge at the intersection of animal and human health. Li's research sheds light on the virus's behavior and its potential impact on human susceptibility. Ongoing funding and support are vital in advancing our understanding of this elusive pathogen.

 

Photo Credit: gettyimages-d-keine

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